Shape memory polymers (SMPs) are materials capable of changing their structural configuration from a fixed shape to a temporary shape, and vice versa when subjected to a thermal stimulus.The present work has investigated the 3D printing process of a shape memory polymer (SMP)-based polyurethane using a material extrusion technology.Here, SMP pellet
Epidural Analgesia with Ropivacaine during Labour in a Patient with a SCN5A Gene Mutation
SCN5A gene mutations can Passion Flower lead to ion channel defects which can cause cardiac conduction disturbances.In the presence of specific ECG characteristics, this mutation is called Brugada syndrome.Many drugs are associated with adverse events, making anesthesia in patients with SCN5A gene mutations or Brugada syndrome challenging.In Textur
A 3D-Printed helmet for precise and repeatable neuromodulation targeting in awake non-human primates
The application of non-invasive brain stimulation (NIBS) in non-human primates (NHPs) is critical for advancing understanding of brain networks and developing treatments for neurological diseases.Improving the precision of targeting can significantly enhance the efficacy of these interventions.Here, we introduce a 3D-printed helmet designed to achi
Targeting the angiotensin II type 2 receptor (AT2R) in colorectal liver metastases
Abstract Background Blockade of the angiotensin (ANG) II type 1 receptor (AT1R) inhibits tumour growth in several cancers, including colorectal cancer (CRC) liver metastases.While AT1R blockade has been extensively studied, the potential of targeting the antagonistically acting AT2R in cancer has not been investigated.This study examined the effect
Computer-based cognitive rehabilitation program GRADIOR for mild dementia and mild cognitive impairment: new features
Abstract Background The growing number of older people and, with it, the increase of neurological impairments such as dementia has led to the implementation of the use of computer programs for cognitive rehabilitation in people with dementia.For 20 years, we have been developing the GRADIOR cognitive rehabilitation program and conducted several stu